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Re: Which benzo with short half life?

Posted by Melusine on October 28, 2017, at 14:01:17

In reply to Re: Which benzo with short half life?, posted by Lamdage22 on October 26, 2017, at 9:46:17

Depends what you need it for, and how you're planning on taking the drug. The route of administration also affects the duration of action. Some benzos can be delivered by routes other than orally.

Also, there are multiple different types of half-lives, and none of which is the sole determinant of duration of action. Elimination half-life (which is usually what is meant by "half-life" if type is not specified) is itself quite variable. It can be affected by other drugs you're taking, if you've eaten recently, genetic variations in can see why it's so variable.

Oh, and it also matters what country you're in. Certain benzos aren't available in some countries. For example, I'm not sure whether you can get oral midazolam in the States. I've only ever heard of it being used in the USA either as part of a general anaesthesia cocktail, or for sedating patients who need to be mechanically ventilated.

I'd probably suggest either alprazolam, or taking lorazepam somewhat earlier than you ordinarily would, so that it wears off by the time you need it to. What dose of lorazepam do you take?





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