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Studies to show doc for shorter MAOI)MAOI washout?

Posted by PeterMartin on September 7, 2017, at 16:36:38

I need to switch from Marplan to Parnate (or maybe Nardil) due to an upcoming insurance change.

I asked my doctor once a while back about whether or not he'd require a washout if I were to switch from Marplan to Nardil. After first thinking one wouldn't be needed he looked it up in a book (oldschool) and said well it probably would be needed.

In the past I know I've switched from Parnate to Marplan w/ only a few days completely off meds. And I'm not really worried about side effects since I'm on moderate dose of Marplan (30 when 40 is the recommended min) and I'd be going to a low dose of Parnate (I'm guessing 20 to 30).

Is anyone aware of any pubmed studies or articles that support a shorter than 14day washout when switching from one MAOI to another? I would hope to use this info to at least cut down the time. The risk of depression relapse is more of a concern to me than elevated bp. I have a bp cuff and would surely be monitoring....

Thanks for any info.

BTW I think this link lets you posts new threads for anyone having issues:




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