Posted by SLS on March 14, 2016, at 13:21:28
In reply to Re: methylation hypothesis, posted by linkadge on March 13, 2016, at 19:33:20
> But, if methylation decreases gene transcription, how does this improve depression?
BDNF is one example of a histone induced epigenetic change in gene transcription that results in a reduction in BDNF synthesis.
This is why I was curious as to whether there were a way to reduce methylation. Does desipramine do this? I'm taking desipramine and lithium.
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1087015
URL: http://www.dr-bob.org/babble/20160306/msgs/1087122.html