Psycho-Babble Medication | about biological treatments | Framed
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You talk awesome

Posted by meffect on August 19, 2015, at 19:49:38

In reply to Re: Is Viibryd or Brintellix 'energizing'??, posted by Louisiana Sportsman on April 19, 2014, at 16:46:04

> > Hello.
> >
> > My diagnosis has always been major depression and the primary symptom I suffer from is a lack of energy, a sort of enervated fatigue.
> >
> > Can anyone say if either Viibryd or Brintellix are "energizing" or "activating" (as opposed, to say, "sedating)?
> >
> > Thank you.
> >
> >
> I am disqualified to deliberate vilazodone [Viibyrd (Forrest)]; contrary, au courant is Day 46 of vortioxetine [Brintellix (Lundbeck)] 1TPOQAMCF; Days 1-29, I administered 10mg., and for the past 17 days, 20mg. I can felicitously share my introduction to vortioxetine.
> I have not experienced any aggrandizement of sedation since initiation. Due to 5-HT3 antagonism, there is a negligible release of histamine (sedating neurotransmitter), but it seems to be off set by the concomitant dopamine and norepinephrine release.
> In terms of activation, I generally prefer for my medications to be energizing as well. My prior ADs were Zoloft (most DA release of the SSRIs) and Effexor/Pristiq (NE reputake inhibition). Antidepressants, besides MAOIs, bupropion (Wellbutrin) and possibly NE heavy desipramine, are generally not something someone takes for the energizing effects.
> One of my PDOC's main concerns when prescribing Brintellix was possible sedation due to my treatment resistant bipolar anergic depression and ADHD. She said it would not likely be a factor she was right. If anything, it is an activating AD since I am able to take in the morning (I prefer to take all my medication in the morning, if reasonable), and it has treated me well.
> To elucidate, I rank Brintellix among the ADs I've been on. I put wayy too much thought into this, by the way. :D
> Zoloft: 8.1/10
> Wellbutrin XL 450mg. (Aplenzin 522mg.): 6.0/10
> Pristiq 50mg. (Effexor XR 75mg.): 6.7/10
> Brintellix: 8.9/10
> Verdict: Neither sedating, not activating unless you want to count relief which translates to more activity. A good AD, but I suggest:
> Try Brintellix only after you have failed a proven SSRI and two other antidepressants from two different classes. If an AD is tolerated, then that AD should be augmented with an atypical antipsychotic before trying Brintellix. Something like: Cymbalta -> Paxil -> Lexapro + Abilify AND then Viibyrd or Brintellix can be justified, and I would still hypocritically recommend a researched AD instead.
> Good luck!

dude... I wish i could talk like you. I love big words that have thoughtful expressive meaning




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