Posted by Lou Pilder on July 24, 2015, at 19:41:08
In reply to Read. » Lou Pilder, posted by SLS on July 24, 2015, at 18:58:31
> Strattera = atomoxetine
>
> http://www.ncbi.nlm.nih.gov/pubmed/15554766
>
> "A MEDLINE search was conducted for articles published from 1962 to December 2003 using relevant search terms (psychostimulant, stimulant, amphetamine, dextroamphetamine, pemoline or methylphenidate, atomoxetine, bupropion, monoamine oxidase inhibitor, and selegiline)."
>
> "No documented reports were found in the recent literature of hypertensive crises or fatalities occurring when the stimulant was cautiously added to the MAOI."
>
> I performed my own searches and was unable to find a single case of adverse reaction attributable to the combination of Strattera (atomoxetine) with tranylcypromine. It is understandable that the drug company for Strattera (Lilly) would want to unconditionally contraindicate combinations of its drug with MAOIs. Older medical literature clinged to the notion that one could not combine MAOIs with any other antidepressant or stimulant. In real life, this has since been shown to be erroneous. The most important adverse reactions occur with drugs that potentiate serotonin neurotransmission, such as SSRIs and SNRIs. This includes the tricyclics: imipramine and clomipramine.
>
> Also:
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> http://www.ncbi.nlm.nih.gov/pubmed/7931221
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> "These results suggest that reboxetine might be advantageously combined with tranylcypromine, or any MAO inhibitor..."
>
>
> - Scott
Scott,
I read that and Strattera is not a stimulant according to my research. In other studies it was Ritalin and Adderall that were cited. And anyway, the article admits that the treatment has risks and just because in their search they did not find deaths, that does not mean that the combination is not contraindicated, for it is and the study was from years ago and there is new additional information available today that was unbeknownst to then. And readers, if taking a combination of drugs is contraindicated, that means the combination is not to be prescribed. I agree that in cases where there is no hope, like last stage cancer, any treatment could be used for there is nothing to loose. But now there are oncologists that do not use chemo in end stage cancer because it could make the patient worse. If there are psychiatrists still using Parnate with Strattera, I do not know of any reports of such in the present. I agree that there could be those in 2003 and such. But that was one-upon-a-time, and once-upon-a-time I havn't seen to come again.
If you want readers to take the two drugs together, if they die from the drugs, their blood will not be upon me.
Lou
poster:Lou Pilder
thread:1080645
URL: http://www.dr-bob.org/babble/20150629/msgs/1080752.html