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Re: Possible drug approaches to hit Glutamate?

Posted by porkpiehat on May 8, 2015, at 11:56:53

In reply to Re: Possible drug approaches to hit Glutamate?, posted by SLS on May 6, 2015, at 11:24:25

> Lamotrigine (Lamictal) reduces glutamate efflux, perhaps secondary to the inhibition of sodium channels and could possibly inhibit AMPA receptors in limbic structures (ventral striatum). One researcher has indicated that N-acetylcysteine (NAC) can augment lamotrigine.
>
> - Scott

Scott I am thinking about adding sarcosine/NAC based on someone's suggestion that my feeling during days after of well-being is coming from a glutamate rebound. HOWEVER I'm currently taking lamictal...do you know if taking them both at the same time is dangerous or pointless?

Thanks


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poster:porkpiehat thread:1078701
URL: http://www.dr-bob.org/babble/20150407/msgs/1078779.html