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Adding low dose Nortrityline to Prozac

Posted by BusuB on March 20, 2014, at 18:02:20

I've been on 10mg Prozac for PD for the last 9.5 weeks and was still having difficulty sleeping and breakthrough anxiety. I'd been taking 50mg Trazodone for the sleep part which was nice but left me incredibly groggy. When I called my pdoc for a refill, he suggested 10mg Nortriptyline, which I've done for the last 3 nights. While I have been sleeping through the night (as predicted by pdoc), I notice that I've been feeling extra edgy lately as if I'd consumed too much caffeine.

Can this be an effect of the Nortriptyline, even at such a low dose? Also, I understand that Prozac slows the metabolism of Nortriptyline to a certain extent, making lower doses more potent. Does anyone know how much more potent Nortriptyline becomes in this instance?


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poster:BusuB thread:1062878
URL: http://www.dr-bob.org/babble/20140307/msgs/1062878.html