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Re: solution? Re: Modafinil only worsens my depression » SLS

Posted by Franz on March 9, 2014, at 13:12:04

In reply to Re: solution? Re: Modafinil only worsens my depression » Franz, posted by SLS on February 17, 2014, at 14:24:54

> > Wow. I did a search on "modafinil depression" on this site and came to this thread. I have similar effects. First 50-100 mg are good (more alert, talkative, but not much motivation) but at the end of the day I feel bad. Dyshporic is a good term as mentioned. Bad thoughts, pessimistic, guilt, etc. Of course my Dr and psychologist do not understand. Most stimulants (caffeine, I have not tried many) let me tired, but this one has a plus of sadness.
> >
> > Anyone can give an explanation? I read that it raises all neurotransmitters except GABA, which lowers. I take a small dose alprazolam at night. Maybe more benzo during the day can help or will that negate the effects of modafinil?
>
> I would consider discontinuing the modafinil. I doubt that there is any kind of trick you can use to reverse your negative reaction to it. Perhaps microdoses? Modafinil affected me in much the same way as it did you. In fact, it left me more depressed and in a brain fog for a few weeks after discontinuation. I now use Focalin (dexmethylphenidate) for days when I am especially anergic and demonstrate cognitive slowing and flat affect. It works pretty well. For me, the onset of clinical effect occurs approximately one hour after the dosing, and lasts for about five hours.
>
> Have you tried Parnate, Effexor, or Wellbutrin?
>
>
> - Scott

I tried modafinil again, small 25-50 mg.

I took care to have tea instead of coffee because I notice caffeine increases anxiety on modafinil, but I need some.

I find that modafinil gives me energy e.g. I can put more effort and do tasks I have to do, like if I put a little willpower I feel that I can do it. After three days the same weir mood returned, like a tense or anxious feeling with dark thoughts, also last night it was very difficult to fall asleep.

I wish this worked better. Maybe I try it each other day.

 

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