Posted by linkadge on July 22, 2013, at 13:46:55
In reply to Trending...'Misery Molecule', posted by brynb on July 22, 2013, at 13:05:19
This is not really a new target. CRF1 receptors are modulated during postive response to a variety of AD treatment. Drugs like tianeptine, TCA's, mirtazpine and ECT have a more profound effect on the HPA axis and CRF1 receptors.
RU486 was a drug that was supposedly being 'fast tracked' for psychotic depression. This was over a decade ago. It acts directly on CRF receptors.
Linkadge
poster:linkadge
thread:1047618
URL: http://www.dr-bob.org/babble/20130706/msgs/1047623.html