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Re: question for SLS re: minocycline

Posted by g_g_g_unit on May 19, 2013, at 6:45:59

In reply to Re: question for SLS re: minocycline » g_g_gunit, posted by SLS on May 18, 2013, at 17:35:41


> >
> > do you believe it has the potential to show anti-depressant efficacy when NOT used in conjunction with lamitrogine
>
> Yes. Minocyline does a bunch of stuff besides reducing glutamate activity. It is hard to know what properties are important in the treatment of depression. Besides, its antiglutamatergic properties are substantial at multiple sites, even in the absence of lamotrigine. For OCD, one might speculate that combining memantine with minocycline would have a synergistic effect.
>
> I am not familiar with any psychotropic effects that Augmentin might have. The cool thing is that minocycline is used to treat Lyme Disease. So, if that is a concern of yours, you would be attacking your condition(s) from multiple angles.
>

Thanks for your response. I've found a GP who's willing to trial an antiobiotic. One paper I came across suggested Augmentin has similar glutamate-modulating properties, but perhaps Minocycline would be a better place to start given its proven efficacy in treating depression.

Just one other point you may have missed in my original post - has Minocycline had any impact (beneficial or otherwise) on your anxiety, pending that's a fact of your condition?

 

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poster:g_g_g_unit thread:1043862
URL: http://www.dr-bob.org/babble/20130501/msgs/1043905.html