Posted by Scars R. Stories on April 2, 2013, at 19:29:52
In reply to Re: Long-term antidepressant studies, posted by linkadge on April 2, 2013, at 19:05:55
> Remeron can be an extraordinarily effective antidepressant in individuals who are otherwise unresponsive to monoamine reuptake inhibitors.
>
> I remember a study suggesting that those with the SS (loss of function) version of the serotonin transporter, responded better to mirtazapine than SSRI.
>
> If you have the SS variant of the serotonin transporter gene, your baseline reuptake of serotonin is already low, producing elevated activation of serotonin receptors in the amygdala (hence an elevation of stress response seen in these individuals).
>
> I have found mirtazapine very effective in reducing generalized fearInteresting! How is SS tested for?
Re: fear, I would have to say again, "because it is sedating", like benzodiazepines but with a host of unpleasant side effects.
poster:Scars R. Stories
thread:1041418
URL: http://www.dr-bob.org/babble/20130322/msgs/1041565.html