Posted by Trotter on December 31, 2012, at 13:23:18
In reply to Re: Bifidobacteria reduce depression, posted by SLS on December 31, 2012, at 7:16:26
> Are there differences in the composition of the endotoxins coming from the upper GI versus the colon?
At a guess I would say there are different, since it seems the endotoxins from the upper GI are from food, and from the colon from resident bacteria. However I have no actual evidence to back this up.
Is there any way to track some sort of endotoxin molecular signature?
Yes. I remember reading somewhere that they tracked an ingested endotoxin into the blood plasma. From memory it was radioactive, but not sure. Further, they can measure antibodies to specific bacterial LPS.
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> Also, have you guys come to any conclusion as to which process allows endotoxins to exit the bowel - transport or translocation?I think it is always translocation. Fat seems to facilitate translocation of LPS. This has been referred to as 'transportation', as the LPS is carried by the fat, but it still involves translocation across the intestine wall.
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> Do all endotoxins produce exactly the same immune reaction, or are there differences in the types and ratios of interleukins, cytokines, and interferons?I'm not sure, but I have not come across any differences, so my guess is that it's pretty much the same.
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> Thanks.
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> - Scott
poster:Trotter
thread:1033371
URL: http://www.dr-bob.org/babble/20121231/msgs/1034288.html