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Re: flumazenil is probably acutely neurotoxic » phidippus

Posted by SLS on September 11, 2012, at 19:54:48

In reply to Re: flumazenil is probably acutely neurotoxic » SLS, posted by phidippus on September 11, 2012, at 17:28:06

> "administration of the benzodiazepine receptor antagonist flumazenil (4 mg/kg, IP) elicited a marked increase (95 or 60%) in dopamine release in the nucleus accumbens"
>
> That's a huge increase in dopamine.
>
> Eric

That might be supportive of what Linkadge often says about too much dopamine activity in certain regions of the brain causing rather than relieving depressive symptoms. I guess it depends on the circuitry.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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