Posted by rovers95 on September 11, 2012, at 10:08:10
In reply to Re: minocycline...the other side of the coin » rovers95, posted by Emme_v2 on September 8, 2012, at 19:54:30
> > Hi, having read (and been delighted by) Scott and Emme's rather encouraging results on minocycline I decided to try myself to treat ongoing low mood/apathy.
> >
> > Unfortunately after two nights taking just 50 and then 100mg I have had to give up (temporarily) due to terrible anxiety, insomnia, nausea and low mood. I have read things regarding a herxeimer reaction to such drugs but it is hard for me to discern (a) does such a thing exist and (b)what is a herx reaction and what are merely side effects.
> >
> > Thinking of starting again but it is a bit worrying when this kind of thing happens! Please note that my reaction may not be typical (although I have read similar anecdotal cases) I often have bizzare reactions to drugs and have CFS type things going on as well.
> >
> > Regards
> >
> > Rover
>
> Hi. A Herxheimer reaction, such as what is experienced by Lyme disease sufferers is related to the release of toxins from bacteria killed by the drug. (From what I've seen in people I know, a Herx reaction can be nasty.) Use of minocycline for unipolar and bipolar depression is based on properties other than its antibiotic capabilities.
>
> Do you have reason to think you might be suffering from Lyme disease or some other spirochete? If not, I don't think what you are experiencing is a Herxheimer reaction but probably side effects from the drug.
>
> You might be starting too high. I had terrible anxiety my first couple of days at 100 mg. I dropped down to 25 mg and after a couple of weeks went to 50 mg. So far so good (*very* good). Have you talked to your doctor about this? I assume your doctor prescribed the 100 mg? Does he or she have experience with this drug with other patients?
>
> Good luck.
>
>
>
>Thanks for your reply
I am down at 25mg now, hoping to build to 50mg, still had a poor nights sleep at 25, but I'm hoping this will wear off as often things that negatively effect my sleep have a positive effect on my mood.
How long did it take you to feel better at 25mg? I must note that previously I did poorly on both lamictal and NAC, but riluzole was great for me at the time.
Regards
Rover
poster:rovers95
thread:1025155
URL: http://www.dr-bob.org/babble/20120830/msgs/1025376.html