Posted by Emme_v2 on September 8, 2012, at 19:54:30
In reply to minocycline...the other side of the coin, posted by rovers95 on September 8, 2012, at 16:51:32
> Hi, having read (and been delighted by) Scott and Emme's rather encouraging results on minocycline I decided to try myself to treat ongoing low mood/apathy.
>
> Unfortunately after two nights taking just 50 and then 100mg I have had to give up (temporarily) due to terrible anxiety, insomnia, nausea and low mood. I have read things regarding a herxeimer reaction to such drugs but it is hard for me to discern (a) does such a thing exist and (b)what is a herx reaction and what are merely side effects.
>
> Thinking of starting again but it is a bit worrying when this kind of thing happens! Please note that my reaction may not be typical (although I have read similar anecdotal cases) I often have bizzare reactions to drugs and have CFS type things going on as well.
>
> Regards
>
> RoverHi. A Herxheimer reaction, such as what is experienced by Lyme disease sufferers is related to the release of toxins from bacteria killed by the drug. (From what I've seen in people I know, a Herx reaction can be nasty.) Use of minocycline for unipolar and bipolar depression is based on properties other than its antibiotic capabilities.
Do you have reason to think you might be suffering from Lyme disease or some other spirochete? If not, I don't think what you are experiencing is a Herxheimer reaction but probably side effects from the drug.
You might be starting too high. I had terrible anxiety my first couple of days at 100 mg. I dropped down to 25 mg and after a couple of weeks went to 50 mg. So far so good (*very* good). Have you talked to your doctor about this? I assume your doctor prescribed the 100 mg? Does he or she have experience with this drug with other patients?
Good luck.
poster:Emme_v2
thread:1025155
URL: http://www.dr-bob.org/babble/20120830/msgs/1025180.html