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Re: Starting minocycline.

Posted by SLS on September 4, 2012, at 13:15:57

In reply to Starting minocycline., posted by SLS on August 14, 2012, at 9:23:51

My doctor acceded to my request to increase my dosage of minocycline from 100 mg/day to 200 mg/day. I would like to convert a partial response into a full remission.

The current clinical trials of minocycline in the treatment of depression use dosages between 100 - 400 mg/day. I felt it was important to explore a higher dosage now rather than to risk remaining underdosed for an extended period of time. The improvement that I am experiencing is not enough for me to return to work or school, although it has been enough for me to go out more and socialize. I know what "magic" feels like. I believe that I am just on the cusp of a robust antidepressant response. I can be such a dumb optimist sometimes. I keep failing to respond adequately to treatment. You would think I would have learned my lesson by now.

My current treatment regime:

Parnate 80 mg/day
nortriptyline 150 mg/day
Lamictal 200 mg/day
lithium 300 mg/day
Abilify 10 mg/day
minocycline 200 mg/day

If I do indeed respond robustly to the addition of minocycline, I would like to attempt to discontinue Abilify. Besides offending my sense of vanity by causing me to gain 50 pounds, it has raised my triglycerides to over 400 mg/dL.

Hoping and praying...

- Scott

Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw




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