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Re: Starting minocycline Iansf

Posted by SLS on August 25, 2012, at 17:15:23

In reply to Re: Starting minocycline SLS, posted by Iansf on August 25, 2012, at 13:59:35

> One thing I'm not clear on is whether minocycline is meant to be taken continuously as with antidepressants or if it's a one-time intervention.

I would guess that we are looking at using minocycline as a long-term treatment. I have not encountered anything that would indicate otherwise. Currently, there is a study of minocycline in the treatment of bipolar depression using dosages between 100 - 300 mg/day for 8 weeks. I can only hope that they coadminister Lamictal to some of the participants.

http://clinicaltrials.gov/ct2/show/NCT01514422

> Is the theory that there is an underlying systemic infection that needs to be cleared up?

No.

> Or is it that the characteristics of minocycline happen to affect brain chemistry apart from its antibiotic properties?

Yes. I listed some of them in the following post:

http://www.dr-bob.org/babble/20120803/msgs/1023257.html

I am impatient. I am tempted to increase my dosage of minocycline from 100 mg to 150 mg, but I haven't spoken to my doctor about this. I'm just curious to see how much better I can feel at the higher dosage. I don't want to get stuck if I remain underdosed for months.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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poster:SLS thread:1023257
URL: http://www.dr-bob.org/babble/20120818/msgs/1024204.html