Posted by linkadge on August 17, 2012, at 6:44:06
In reply to Re: Advice » don'ttalktome, posted by brynb on August 16, 2012, at 16:12:36
I don't feel that the evidence supports the efficacy of lamotrigine in bipolar disorder.
It does not have antimanic efficacy, and the so called 'anti-depressant' effects are not consistent or reliable.
Its like mixing a benzodiazapine with strong coffee and calling it a mood stabilizer.
GSK performed dozens of studies of lamotrigine in bipolar most of which failed to show superiority over placebo or existing mood stabilizers.
poster:linkadge
thread:1023348
URL: http://www.dr-bob.org/babble/20120803/msgs/1023501.html