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Re: Abilify vs Seroquel Alexei

Posted by tensor on April 25, 2012, at 12:27:46

In reply to Re: Abilify vs Seroquel tensor, posted by Alexei on April 25, 2012, at 11:10:42

> Wow, that is a great link. Some good info. I will give 100mg lamictal one month and then re-evaluate how I feel. It is a very subtle drug, but I think it is helping.
> I switched to abilify because I was too sedated on seroquel. But I now realize that I did not go high enough with the seroquel dose, or do it quickly enough... so the sedation never had a chance to go away.
> I have read the ideal augmenting dose for quel is 200-300. Very little dopamine antagonism at those doses. But abilify can antagonize DA much sooner. Like around 10mg.
> Have you decided what you will do?
> Btw ... Has remeron been a good antidepressant?

Okay, how high did you go on Seroquel? I think my long exposure to Remeron has desensitized me to H1-antagonism, at least to some extent, I mean I do get very tired of Seroquel, enough to let me fall asleep. But it wears of quickly, within a few hours, even with the XR version.
I agree, high doses with Abilify can hardly be justified for MDD, however, I had no luck at any dose up to 15mg. I didn't do well on Seroquel, Abilify or Lamictal on their own (+ some ADs), but now with two weeks on Lamictal and Seroquel I have had the best day today probably for over a year, I've got a lot done, and I wanted to, wasn't forced. There seems to be something about the AAP + Lamictal combo, I think it was Scott (SLS) who suggested it to me.
I have decided to stay on Seroquel for now, since I will step up to 100mg Lamictal tomorrow, I won't touch the dosage either. Since I'm doing okay it's wisest to do only one change at a time.
Remeron, well I'm not so sure why I'm taking it anymore, but I always seem to do worse without it, so I'm keeping it just to be 'safe'. It was the first antidepressant I responded to and it completely wiped out my depression.





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