Psycho-Babble Medication | about biological treatments | Framed
This thread | Show all | Post follow-up | Start new thread | List of forums | Search | FAQ

Lou's reply-agranulocytosis » SLS

Posted by Lou Pilder on February 27, 2012, at 22:10:29

In reply to Re: Lou's request-fenfluramine, posted by SLS on February 27, 2012, at 21:57:09

> > Now in relation to saphris, as to what the drug is and such, and what it can do to the taker of the drug, I would like to introduce in the expsition the drug known as {Fenfluramine}.
>
> Okay.
>
> > Now another drug called {phentermine} combined with (fenfluramine), gives a drug called Phen-fen.
> > This drug has been taken off the market
>
> Also, fenfluramine itself has been taken off of the market.
>
> > because of how it could cause heart disease and death.
>
> Yes. Valvulopathy. Also, pulmonary hypertension if my memory serves me.
>
> Fenfluramine is a dangerous drug.
>
> > Now the drug Saphris activates in one way or another some of the same receptors as fenfluramine.
>
> To the best of my knowledge, this is misinformation.
>
> Fenfluramine is a serotonin releaser that activates many different serotonin (5-HT) receptors. Asenapine acivates only one serotonin receptor - 5-HT1a. The mechanism by which fenfluramine causes adverse heart effects is via 5-HT2b receptor activation. Saphris and fenfluramine are not alike in this respect.
>
> > So if you read the Saphris PI there could be the disclosure of possible agranulosis.
>
> To the best of my knowledge, agranulocytosis is not an adverse effect of Saphris.
>
> Agranulocytosis is listed on the PI only because other drugs in its class have this side effect. Can you prove that a single case of agranulocyctosis has occurred with Saphris? I couldn't find a single case on Medline/Pubmed.
>
> > In the clinical trials, there were many deaths.
>
> To the best of my knowledge, this is misinformation.
>
> Please provide citations for this statement.
>
> Your use of the word "many" is an exagerration.
>
> To the best of my knowledge the 3-post rule still applies. Life is good.
>
>
> - Scott

Scott,
https://www.druginformer.com/search/side_effect_details/saphris/agranulocytosis.html

 

Thread

 

Post a new follow-up

Your message only Include above post


Notify the administrators

They will then review this post with the posting guidelines in mind.

To contact them about something other than this post, please use this form instead.

 

Start a new thread

 
Google
dr-bob.org www
Search options and examples
[amazon] for
in

This thread | Show all | Post follow-up | Start new thread | FAQ
Psycho-Babble Medication | Framed

poster:Lou Pilder thread:1011122
URL: http://www.dr-bob.org/babble/20120221/msgs/1011866.html