Posted by SLS on February 21, 2012, at 5:38:42
In reply to Re: Depakote and sleep » SLS, posted by g_g_g_unit on February 21, 2012, at 4:15:33
> > If Parnate is to be your miracle drug, you might have to deal with severe insomnia. This is something that must be dealt with aggressively and should not be the reason to discontinue treatment if at all possible.
> Thanks Scott. I'm actually getting a little worried thinking about the whole sleep issue.
> I can't tolerate benzos (rebound depression), Gabapentin (increased depression), or Seroquel (restless leg syndrome) and I grow tolerant to anti-histamines very quickly (within a matter of days), so that doesn't seem to leave too many options .. unless I look into a long-acting benzo like Klonopin (the half-life of which might help mitigate next-day withdrawal issues), or, as I've mentioned, clonidine, though the reports in the archive don't seem too favorable.
Are you currently employed? If not, then you might have the luxury of time in performing the experimentation necessary to titrate Parnate and find a treatment for the insomnia.
You sure are a challenge. Yes, Klonopin was the first drug that came to mind. I did well with it years ago when my Parnate insomnia was very bad. Trazodone should be considered also. I wouldn't worry too much about hangover effects right now, which you might get from trazodone. You can mitigate this through dosage adjustments as the body accomodates to it. Linkadge has found the combination of melatonin, cyproheptadine, and Ativan effective.
Can you list which hypnotics you have tried already? Can you describe the withdrawal effects you get?
> Do you find that Prazosin helps with sleep-onset at all?
I really can't say for sure. I didn't have a problem with sleep initiation to begin with with. I believe prazosin has smoothed out my sleep with fewer awakenings. I also fall asleep faster after an awakening. Sigismund might try prazosin for his sleep issues. I'll be curious to see what happens with him.
Take things one step at a time, and start a new thread regarding treating your Parnate-induced insomnia.
Some see things as they are and ask why.
I dream of things that never were and ask why not.
- George Bernard Shaw