Posted by Solstice on February 19, 2012, at 23:22:53
In reply to Re: Desperate » SLS, posted by SLS on February 19, 2012, at 21:25:54
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> One more tool to be aware of is Topamax. It works for mixed states, as does Depakote. Topamax treatment must be initiated at a very low dosage and titrated gradually in order to avoid cognitive side effects. 100 mg may be all that is needed. I have seen it work wonders for mixed states. Topamax is known to produce weight loss, just in case that is an issue.
Scott -I read some patient dialogue about Topamax, and they discussed whether slow titration serves to minimize cognitive side effects. Some thought that slow titration did not minimize cognitive impairment, but rather masked it because it was less noticeable when the decline built more slowly.
I cannot judge the validity of their statements, but I am very interested in what you think about the merits.
Also - one of them said they switched to Zonegran, which supposedly did not have the cognitive impairment side effect. We just need to be careful about trying anything that is known to make irritability/agitation worse.
Solstice
poster:Solstice
thread:1010739
URL: http://www.dr-bob.org/babble/20120212/msgs/1010908.html