Posted by Chairman_MAO on October 1, 2011, at 15:29:14
In reply to Re: 'Pulsing' Wellbutrin Dose, posted by SLS on September 29, 2011, at 17:21:43
> Throughout my treatment history, it was recommended by doctors that I NOT pulse antidepressants. I am not sure of all their reasons why, but I think treatment resistance was a concern.There's an exception to [nearly] every rule, but there are myriad reasons for this. I'm sure your familiar with a lot of them.
This is one reason: http://en.wikipedia.org/wiki/Kindling_(substance_withdrawal)
This is a neurological term used when talking about seizures, but it very well could apply here.
I think there is also a danger with certain agents of inducing bipolar disorder/mood swings.
Bupropion does have long-acting metabolites, though, and you could stagger doses just to get low levels of the long-acting ones (maybe? I really dont recall enough about it to tell you offhand).
In the final analysis, whatever works for you is what works for you, but I think most likely you're at best going to end up with a suboptimal solution.
poster:Chairman_MAO
thread:997996
URL: http://www.dr-bob.org/babble/20110925/msgs/998474.html