Posted by europerep on July 18, 2011, at 5:45:34
In reply to Re: cannabanoid CB1 agonists are neuroprotective » europerep, posted by linkadge on July 17, 2011, at 22:21:16
> Not really. In order for CB1 receptor signaling to take place, you need a CB1 agonist of some form.
>
> LinkadgeAt best, the research shows that AEA, 2-AG and other endocannabinoids are neuroprotective. It doesn't say anything about whether administration of, say, THC would have neuroprotective effects. Besides, I don't think that, if lack of CB1 signaling causes memory deficits and so on, this automatically means that introducing exogenous CB agonists in a healthy individual will be neuroprotective. It may be, but that's not what the research aims to show I think.
poster:europerep
thread:991238
URL: http://www.dr-bob.org/babble/20110714/msgs/991301.html