Posted by mtdewcmu on April 1, 2011, at 0:57:44
In reply to Re: Alpha-delta sleep and cymbalta? » desolationrower, posted by Christia on March 31, 2011, at 22:25:01
> This site is great! So much knowledge. I have to look up 5ht2c and 5ht2a to see what they are. Had to look up cyproheptadine as well. WOuld this be to improve sleep?
Here's what I know about 5-ht2a/c in a nutshell:
5-ht stands for serotonin, which is also known as 5-hydroxytryptamine.
5-hta/c are 5-ht receptors. So they are like buttons that are pressed by 5-ht. Having lots of 5-ht around due to an SSRI means they get pressed more often. Here's what they do:
5-ht2a is the receptor for psychedelic drugs and causes hallucinations. Newer antipsychotics block it.
5-ht2c is thought to cause a lot of SSRI side effects, like anxiety and agitation.
Blocking those receptors is thought to have an antidepressant effect.
Actually, that's not *everything* I know, but that's what's pertinent to the discussion.