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Re: Advice please re. clomipramine/anafranil

Posted by creepy on January 19, 2011, at 11:24:40

In reply to Re: Advice please re. clomipramine/anafranil, posted by Gab2010 on January 11, 2011, at 14:25:07

I have read other posts from people having increased pain perception with prozac (say that 5 times fast!). I also read somewhere that the number of opioid receptors increased during prozac treatment. So you may be on to something.
There are other ADs out there which may help and have the benefit of reducing pain as well. Typically the SNRIs are recommended for depression with pain. But people with pain resulting from depression itself (liek me) will probably benefit from anything that alleviates depression.
Im not a fan of the SNRIs due to the discontinuation effects and short half-life.
If you want to take a second drug to augment the antidepressant and help pain, desipramine is good stuff.
If you want to move to another AD, I know Ive had wonderful results with PTSD by taking lexapro and zoloft. Clomipramine will have a lot more side effects but the TCAs may work better on anxiety symptoms. Depends on your individual response.
My doc says shes seen many people with PTSD hyper-respond to meds and have more side effects. She doesnt think its all psychosomatic either.

 

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