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Re: Vilazodone vs Nefazodone - 5-HT receptors

Posted by linkadge on November 14, 2010, at 7:56:17

In reply to Re: Vilazodone vs Nefazodone - 5-HT receptors, posted by SLS on November 14, 2010, at 3:11:26

>Maybe Linkadge can offer an opinion as to what >roles melatoninergic activation would play in >the pro-sexual and antidepressant effects of >agomelatine

I think I agree with you on the 5-ht2c thing. Animal studies seem to suggest that the combination of 5-ht2c antagonism and 5-ht2a *agonism* is prosexual.

However, there was one animal study I read which showed that melatonin administration was able to preserve the sexual activity of animals who were under stress.


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URL: http://www.dr-bob.org/babble/20101107/msgs/970182.html