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Re: Study: Reboxetine found ineffective,may be harmful » SLS

Posted by linkadge on October 15, 2010, at 16:40:35

In reply to Re: Study: Reboxetine found ineffective,may be harmful, posted by SLS on October 13, 2010, at 6:15:25

>My impression of reboxetine, all in all, is that >it is not as effective as the tricyclics, >despite robust NE reuptake inhibition >properties. Regarding the selectivity of these >drugs for NE, desipramine works. Strattera >doesn't. I don't think reboxetine does either.

Norepinephrine reuptake inhibition is probably not relavant to the effects of any antidepressant IMHO.

Why a potent selective NRI like straterra or reboxetine is not an antidepressant seems to argue that norepinephrine reuptake inhibition is of little theraputic relavance.

Linkadge



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