Posted by SLS on October 14, 2010, at 18:05:18
In reply to Re: Study: Reboxetine found ineffective,may be harmful » SLS, posted by Jay_Clockwork_Angels on October 14, 2010, at 11:44:13
> > I couldn't find it in the article. What were the harmful effects that were referred to?
> > I had a terrible reaction to reboxetine. It produced a suicidal state with anxiety. I try not to generalize my experiences to others, though. However, I have not seen more than a handful of people take reboxetine while posting on Psycho-Babble. I think one person had a robust response. However, I think that the population of posters here is weighted towards people from the US, where reboxetine is not available. My impression of reboxetine, all in all, is that it is not as effective as the tricyclics, despite robust NE reuptake inhibition properties. Regarding the selectivity of these drugs for NE, desipramine works. Strattera doesn't. I don't think reboxetine does either.
> I don't like to generalize and I hate making assumptions (not good science..lol) but from my anecdotal evidence, and seeing a number of posts regarding Strattera and Reboxetine, it seems some of the NE reuptake inhibitors can create a bit more risk of suicide. I think it may be the initial more activating factor.
> I wonder how they compare when added to an SSRI, as I imagine you may get a good response with the dual reuptake inhibition. One med I am thinking of adding to my Prozac is maprotiline. Desipramine did not provide much in the way of depression relief for me.
> Current meds:
> Prozac 80mg qd
> Lyrica: 150mg bid
> Topomax: 100mg bid
> Risperidal: 1mg bid
> Clonazepam: 1mg qid
Do you ruminate much? Looking at your medication, it would seem that you are fighting against obsessions, rumination, and social anxiety. That's a rough guess, but I am curious as to what you are attempting to treat. I like Topamax. I have seen it work wonders for mixed-state bipolar disorder. Where does it fit in your treatment?
The measure of achievement lies not in how high the mountain,
but in how hard the climb.
The measure of success lies only in how high one feels he must
climb to get there.