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Re: going back to bipolar medications

Posted by SLS on October 12, 2010, at 7:57:08

In reply to Re: going back to bipolar medications, posted by bleauberry on October 12, 2010, at 5:36:52

> I'm not a fan at all of lamictal. It seldom seems to lead to any of kind of lasting benefit,
not even in clinical trials,

How do you account for the people who do respond well to lamotrigine treatment for depression, especially in polypharmacy? That would include me. Are the antidepressant effects of lamotrigine limited to bipolar disorder? Perhaps not. I think there needs to be more study in this area to characterize lamotrigine therapeutically, and to elucidate its mechanisms of action. Whenever I try to lower the dosage or discontinue lamotrigine, I feel significantly worse. In other words, repeated challenges with the higher dosages of lamotrigine procuced therapeutically measurable improvements in my depression. It is difficult to completely ignore real-life anecdotal experiences.

I would like to see how well unipolar depressives respond to a combination of lamotrigine with either Wellbutrin or Parnate.


- Scott


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but in how hard the climb.

The measure of success lies only in how high one feels he must
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