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Re: Agomelatine add-on to Nardil » ed_uk2010

Posted by Ron Hill on August 16, 2010, at 18:05:25

In reply to Re: Agomelatine add-on to Nardil » Ron Hill, posted by ed_uk2010 on August 15, 2010, at 7:06:30

Ed,

> Glad that agomelatine is helping.

Thanks. I forget if I said it above, but Valdoxan (agomelatine) is tx for my circadian rhythms which, in turn, is an effective tx of my bipolar II disorder and my associated ultra rapid cycling. I'm only two weeks into my Valdoxan trial, so it's too soon to predict the long-term effectiveness. But, so far, it "feels" very good.

> Will you stay at 25mg?

I hope I won't need 50 mg/night due to the cost.

> I imagine you are paying a lot for it even at this dose.

Not bad for a new medication, but expensive because my insurance company does not pay for meds that are not U.S. FDA approved. 28 tabs of 25 mg each costs $90 plus $7 shipping.

> Which country has it come from? UK?

My p-doc and I obtain three months supply per order from an on-line pharmacy in accordance with U.S. FDA rules. I don't know which country the pharmacy gets it from, but they arrive sealed in the original Valdoxan boxes. The on-line pharmacy is very trustworthy but, of course, I can't give the URL on this site.

>> 500 mg/day of Keppra is very beneficial to me. However, 1000 mg/day causes depression.

> What symptoms does it help?

Moodstabilization and antidepressant. The latter surprised me. But according to my mood tracking chart, it's true.

> Have you tried 250mg per day? eg. 125mg BID.

Yes, but the antidepressant effect is reduced.

> > 300 mg/day of lithium carbonate

> Have you tried lithium before? I can't remember.

Yes, I took it for many moons about 10 years ago. It provides mood stabilization at about 600 mg/day. But, AED's are the better moodstabilizers for me as a Bipolar II. Lithobid never provided any antidepressant effect for me. I want to add 300 mg/day primarily for its neurotrophic benefits.


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URL: http://www.dr-bob.org/babble/20100811/msgs/958856.html