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Re: Agomelatine add-on to Nardil » inanimate peanut

Posted by Ron Hill on July 2, 2010, at 2:03:13

In reply to Re: Agomelatine add-on to Nardil » Ron Hill, posted by inanimate peanut on July 2, 2010, at 1:16:05

> Please keep us posted if/as you try this.
----------------

Inanimate Peanut,

Will do.

I see my p-doc on 7/7/10 to present my research. Nowhere, absolutely NOWHERE, have I found any statement saying that agomelatine and MAOI's are contraindicated.

But, a lot of p-docs run the red flag up the pole and plug their ears when the patient says the all dangerous word; MAOI. MAOIs demand respect and wisdom, but they are powerful meds; albeit with a lot of side effects.

Clearly, adding agomelatine with Nardil has risk. But, if done very carefully, a prudent patient and p-doc can use very small doses with rigorous blood pressure monitoring to determine a safe dosage (if any). The combination clearly needs to be treated with respect, in the same way that adding a pstim to an MAOI must be treated with respect.

As I'm sure you know, Parnate is typically more prone to producing a hypertensive crisis than Nardil. So, even if I do find success combining agomelatine with Nardil, that does not mean it can safely be combined with Parnate.

Nice talking to you, IP. I will post if I am allowed to give the combination a trial.

-- Ron


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poster:Ron Hill thread:952388
URL: http://www.dr-bob.org/babble/20100628/msgs/952925.html