Posted by linkadge on April 10, 2010, at 16:19:11
In reply to TCA's With Opioid Actions?, posted by bulldog2 on April 10, 2010, at 11:52:22
The TCA's have direct effect on opiate receptors: genererally, delta and kappa, with some mu interaction(?). The noradrenergic TCA's also have indirect effects on noradrenergic function. NRI's apparently prolong the effects of opiate ligands in some way.
Linkadge
poster:linkadge
thread:942955
URL: http://www.dr-bob.org/babble/20100406/msgs/943003.html