Posted by SLS on April 5, 2010, at 7:18:53
In reply to Re: Who's taking Seroquel for (bipolar) depression?, posted by Hombre on April 5, 2010, at 0:46:45
> > > Right now I'm not sure how Remeron and Seroquel are interacting with Effexor. Before Seroquel I tried dropping Remeron to 15mg and felt a slow but steady drop in mood. At least on paper, Seroquel does a lot of what Remeron does, and so along with venlafaxine may complete the (New Wave) California Rocket Fuel combo that seems to have lifted me out of the depression. The only problem is getting a good night's rest.
> > Seroquel does not antagonize NE alpha2 receptors as does Remeron. I don't think there is enough overlap between the two drugs so as to call them equivalent in the California Rocket Fuel regime.
> I thought Seroquel antagonized alpha 1 and alpha 2 adrenergic receptors. Maybe not to the same extent as Remeron or at a clinically significant level.
> In any case, we're going to try 150mg Effexor and drop down to 15mg Remeron with the goal of eliminating it.
>
> The Great Experiment continues...
>
> 150mg venlafaxine XR
> 15mg mirtazapine
> 50mg quetiapine
> 1mg lorazepam
Hi.Good luck with your new treatment regime. As an aside, the major metabolite of Seroquel does inhibit the reuptake of NE. Interesting combo.
- Scott
poster:SLS
thread:938976
URL: http://www.dr-bob.org/babble/20100328/msgs/942292.html