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Re: Who's taking Seroquel for (bipolar) depression?

Posted by Hombre on March 9, 2010, at 20:25:19

In reply to Re: Who's taking Seroquel for (bipolar) depression? » Hombre, posted by Phillipa on March 9, 2010, at 11:59:32

> That's a good question I'd like to follow as took it for a few days and was taken off. Phillipa


From what I hear, many people are put off by the idea if taking higher doses because of the fear of increased sedation and daytime drowsiness. From what I've read, those symptoms may abate at higher doses.

For example, my experience with Remeron (at 15mg was that the first night was the worst, but within a few weeks I got used to the sedation. At 30mg a few weeks later I was sleeping soundly but OK during the day. I should note that it was losing its antidepressant punch by then. By the time I went to 45 ~2 months into it, it barely made me drowsy and there weren't any daytime effects as far as I could tell.

I mention Remeron because I believe it affects H1 receptors and antagonizes one or two of the HT receptors. I believe Seroquel has similar actions, but I defer to those with more specific and accurate knowledge.

 

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