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Re: L-Tyrosine and Parnate

Posted by bulldog2 on January 15, 2010, at 15:09:57

In reply to Re: L-Tyrosine and Parnate, posted by Charles Darwood on January 14, 2010, at 20:22:29

> I think this is of some relevance:
>
> From Birkmayer W, Riederer P, Linauer W, Knoll
> Journal of Neural Transmission. 1984: 59(1):81-7:
>
> "The antidepressive efficacy of 1-deprenyl (5-10 mg daily) plus 1-phenylalanine (250 mg/day) has been evaluated in 155 unipolar depressed patients. Both oral and intravenous administration showed beneficial effects in 90% of outpatients and 80.5% of inpatients. It is concluded that this combined treatment has a potent antidepressive action based on the accumulation of 1-phenylethylamine in the brain."
>
> If it works for selegiline, I would assume it would work for tranylcypromine. However, in my experience, neither DL-phenylalanine nor tyrosine has had much effect on my mood, but maybe I'm just in that unfortunate 10% category. I did stir a gram of phenethylamine into a double espresso once and drank it with parnate and felt a not-unpleasant buzz for a couple of hours.
>
> I have read that increased catecholamine synthesis depresses serotonin levels, so perhaps one should augment with 5HTP as well. By that point, however, it's probably safer to use cocaine.
>
>
>

A Gram of pea!! That would have caused a hypertensive crisis in some.

 

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URL: http://www.dr-bob.org/babble/20100113/msgs/933780.html