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Re: Should I discontinue Adderall as Parnate 'augment' » SLS

Posted by Girlnterrupted78 on November 17, 2009, at 7:50:16

In reply to Re: Should I discontinue Adderall as Parnate 'augment', posted by SLS on November 17, 2009, at 6:13:17

Thank you for your detailed response.

> I have not tried Adderall, but I have tried Dexedrine (d-amphetamine) in combination with Parnate 120mg. I felt a little better for the first few days, but that was it.

That is what worries me. Since I already know that I am completely tolerant to Adderall (I tried it while in college twice, and the most it ever worked was like 2 weeks, then it barely worked, then it stopped competely--and never worked again,) I am concerned that it is in fact doing nothing for me, other than making me even more tolerant to treatment in general, and that would be just fatal in my case, since my resistance to treatment is so high already.

I personally would like to drop it altogether. I'm almost sure it won't make a difference. I remember telling me doctor "What are we going to do if Parnate stops working?" And his answer was "That doesn't worry me in the least, right now I'm more worried about your low bood pressure." And within 2 weeks, Parnate stopped working. I guess from experience I already know how easily I become tolerant to just about any drug, and my guess from day 1 was that Adderall was not going to do anything for me, and I continue to believe that.

"One of the disadvantages of taking amphetamine chronically is that it facilitates neurotoxicity via the loss of DA uptake sites in the striatum and nucleus accumbens. It can also form free radicals because it is very oxidative."

And what would be the consequences of something like that? Is it worth taking the risk, knowing beforehand that I am already immune to Adderall?

How easy is to become tolerant to the other augmenters? Nortriptyline, and the rest that are being used?

Once you become tolerant to everything, is there anything left to try? Or that is simply the end of the journey?

Thanks again for your informed contribution.


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poster:Girlnterrupted78 thread:926000
URL: http://www.dr-bob.org/babble/20091117/msgs/926010.html