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Re: hydromorphone in combination with six other meds

Posted by doxogenic boy on August 19, 2009, at 15:21:33

In reply to Re: hydromorphone in combination with six other meds doxogenic boy, posted by Phillipa on August 17, 2009, at 21:02:37

> Grapefruit juice is contraindicated with a lot of meds is opiods Included? Love Philllpa

I thought grapefruit juice could increase the effect of hydromorphone but I haven't found anything.

http://en.wikipedia.org/wiki/List_of_drugs_affected_by_grapefruit#Affected_drugs

http://en.wikipedia.org/wiki/Grape_fruit#Drug_interactions

Another thing:
Here is an article about opioids and tolerance:
http://bja.oxfordjournals.org/cgi/reprint/81/1/58.pdf

Excerpt from the article:
"The indications are that blocking of opioid tolerance by
NMDA antagonists is not a general phenomenon but appears
selective for tolerance induced by morphine."


doxogenic


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