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Re: Consensus on Mirapex (pramipexole)

Posted by SLS on August 19, 2009, at 5:47:34

In reply to Re: Consensus on Mirapex (pramipexole), posted by Brain Damage on August 19, 2009, at 5:16:16

> Firstly I should say I've never taken Mirapex
> My impresion is that it work ok for a few days then stops working.
> Also can cause "sudden sleep attacks".
> Maybe it works for some people.....
> I personaly think Piribedil is a better bet

I agree with all of this.

Thanks, Brain Damage.

I do know someone who received mild benefit from Mirapex (pramipexole) for almost six months, but this seems to be the exception.

The NIH had run an investigation into the use of Mirapex in the treatment of mood disorders. Nothing seems to have come of it.

Then you come upon studies like these:

There are a bunch more. It is difficult to reconcile the conclusions of these studies with what I have seen personally. I think the bottom line is that if you are running out of options, giving Mirapex or Requip a quick trial might be justified.

Having found this ongoing clinical trial, and in consideration of the previous NIH study, I guess they have found some utility in using Mirapex.

I once tried bromocriptine (Parlodel), another DA receptor agonsist. It helped for 3 days and then quit on me. However, this is also my pattern of response to standard antidepressants.

I guess I raised more questions than I answered.

- Scott




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