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Re: Extreme internal restlessness/agitation!!!! HE » jerrypharmstudent

Posted by SLS on July 28, 2009, at 6:11:43

In reply to Re: Extreme internal restlessness/agitation!!!! HE » linkadge, posted by jerrypharmstudent on July 27, 2009, at 13:52:19

> Saw my pdoc today and he instead wanted to try Geodon. I've gained 20 lbs from the Zyprexa in just 6 weeks. I had a good and very immediate response from Zyprexa so now I'm nervous to be switching. Anything you can tell me about Geodon?

I think there is a trend in psychiatry to use Geodon more often as an augmenter of antidepressants. 80mg was of great help to a friend of mine who is taking Lexapro and Wellbutrin. Zero weight gain. I think 40mg is the dosage most often targeted for depression. I became a bit of a zombie at dosages above 40mg. I would have been much more happy with the drug if the antidepressant response I received from it were to last for more than a week. But my system is notorious for short robust responses. Right now, I am having success with a combination of medications that includes Abilify.

Geodon does a bunch of different things, much of which are antidepressant-like:

5-HT reuptake inhibition
NE reuptake inhibition
5-HT2a antagonist
5-HT2c antagonist
5-HT1d antagonist
5-HT1a agonist/partial agonist
D2 antagonist
NE alpha-1 antagonist


- Scott

 

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