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New mechanism for the AD effect of CAFFIENE

Posted by linkadge on July 1, 2009, at 16:40:10

I was doing a little reading.

Mice that lack the TREK-1 potasium channel exhibit a depression resistant phenotype.

http://www.scienceblog.com/cms/ever-happy-mice-may-hold-key-to-new-treatment-of-depression-11343.html

SSRI antidepressants (and caffiene!) inhibit TREK-1 activities.

http://eprints.iisc.ernet.in/3579/1/A141.pdf

Linkadge


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poster:linkadge thread:904249
URL: http://www.dr-bob.org/babble/20090630/msgs/904249.html