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Re: Is there any hope?-)MAOIs

Posted by desolationrower on April 2, 2009, at 23:58:06

In reply to Re: Is there any hope? desolationrower, posted by Garnet71 on April 2, 2009, at 21:21:29

> >MAOIs. And i suppose i can't help but be biased but i think they are much stronger, and the long-term side effects are lower.
> d/r,
> I could have missed the posts, but I don't see too many taking MAOIs for GAD/panic disorder. Do you mean MAOIs for that too?

yes. They're pretty much the best drug for anxiety/depression type things except for psychotic depression. I don't think theres been much testing on them specifically, some of the specific disorders weren't created until after they had fallen out of favor, and at the time benzos were still considered good treatments, so there wasn't much need for much else for anxiety. Panic used to be treated with tcas and maois.

> It seems to me that most are using those for depression-atypical, treatment-resistant, maybe periphial anxiety; like I said, I could be wrong...but even though depresson/anxiety can be interrelated, it seems to be alot different treating symptoms that manifest mainly as anxiety/panic attacks as opposed to symptoms that manifest mainly as depression.

well the 'atypical' specifier refers especially to 'rejection sensitivity', and some of the evidence for them shows those with comorbid anxiety respond better.

i think phenelzine would be a really good idea, its just not worth it to keep trying drugs that don't work. there might be others (clonidine would be quite good for the fight/flight too, but its not an antidepressant), but its a good antidepressant too. A benzo would work too, but even alprazolam isn't a strong AD, and surely thats been tried by now?





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