Posted by Sigismund on March 12, 2009, at 20:42:48
In reply to Re: crisis mode, posted by elanor roosevelt on March 11, 2009, at 23:11:15
Hi Elanor
I don't take SAMe now, but I have for extended periods over the years.
It can irritate the gut, so there are differing opinions as to whether to take it on an empty stomach.
Doses range from 200 to 1600 mg/d.
Often I would take 400mg first thing in the morning. That is a threshold dose, just noticeable for me, but also useful and not problematic.
It can aggravate insomnia.
(I spend my life trying to figure out my insomnia.
Was it the alcohol, the black tea or the chocolate, or that vitamin B at lunch?)
Which would be why I'd take it first thing.If you need to take a dose of 800 or higher you would be best to split it.
Some people find SAMe agitating.
poster:Sigismund
thread:884182
URL: http://www.dr-bob.org/babble/20090304/msgs/885100.html