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Duloxetine ineffective?

Posted by Pete1968 on January 15, 2009, at 17:29:26

Hi all, I was wondering if anyone else here has had experience of Duloxetine not working?

I have been taking 60mg Duloxetine for a month now after switching from Venlafaxine 150mg, and feel worse than I was on the Venlafaxine. I had hoped Duloxetine would be more effective than Venlafaxine (which I had been on for a year and found to be only partially effective). I thought these drugs were specifically aimed at treatment resistant depression, ie. more effective than standard SSRIs? My experiences with them lead me to believe that an SSRI such as Escitalopram works better for me in alleviating depressive symptoms, however I cannot tolerate the side effects of SSRIs specifically the gastro-intestinal upset.

Has anyone else tried these two SNRIs and found them ineffectual?


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poster:Pete1968 thread:874178
URL: http://www.dr-bob.org/babble/20090104/msgs/874178.html