Posted by JadeKelly on December 8, 2008, at 23:05:13
In reply to Re: Need advice! Nardil switch to Parnate!! » JadeKelly, posted by ParnateStarted2008 on December 6, 2008, at 17:45:14
> > > > Hi Phil,
> > > >
> > > > Actually have only taken 50mg one time yesterday.
> > > >
> > > > > If your feeling ok, how is 50mgs/day Parnate treating you? Do you have the initial "good feeling" from the NE/EPIneph?
> > > >
> > > > Nope. (Only took once yesteday-not sure about it now, help?)
> > > >
> > > > Actually haven't been feeling so great for couple days: Bad nightmare, irritable, sad, crying (not the good kind) OMG!!! FEELINGS!! NO!! Thought I was supposed to feel good. I feel Yuk. That was why I upped to 50mg. Geuss I thought 8 weeks was enough.
> > > >
> > > > >How are the side effects... I may be asking too much here as you just raised it.. Im eager I guess to know your progress. If ya Feel like crapoolliioo dont worry about my questions..
> > > >
> > > > NO, NO! I do feel like crapoolliioo physically and mentally, but tell me I'm normal and this will go away!!
> > > >
> > > > I realized I had been on 30mg/6weeks and 40mg/2weeks (seems like 8 weeks is a while on Parnate) and geuss I panicked and called PDoc. He raised to 50mg. But you said wait 3 weeks on each. Did I make a mistake? Its not too late, I only did it once. I can go back to 40mg for another week.
> > > >
> > > > You, and other poster said its normal to feel wierd, I just don't know if this is "the wierd" or I'm just backsliding and need to keep on 50mg. I feel a bit scared and headache and like I'm going to cry. Not good cry like yours. Don't want to leave my room.
> > > >
> > > > So, up the dose to 50mg?
> > > > Or this is normal and stay on 40mg longer?
> > > > Def got some feelings coming back, but not good ones. (Can I go back to numb pplease?) Ok, more crying this is rediculous.
> > > >
> > > >
> > > > > I got trazodone 50mg at bed time today so Im not taking Zopiclone or Seroquel tonight, and hopefully never again. I guess that cuts 1 pill off my regime.. slow but progress. next is going off Clonazepam...
> > > >
> > > > Good for you!! Lots here take trazodone. I'm geussing it will help you sleep?
> > > >
> > > > Me too, I need off Conazepam. Take for my neck, but maybe a couple right now....JK!
> > > >
> > > > NOT quitting Parnate, its been 8 weeks tho, would love to know if you think I'm on right track/ or this isn't normal and I should feel differently.
> > > >
> > > > > Talk to you later
> > > >
> > > > OK, Phillipe!!
> > > >
> > > > Btw-Phillipa said to mention: you have to let admin know of name change, or you could get block or something. You probably know that.
> > > >
> > > > Thanks for all, hope to hear from you soon.
> > > >
> > > > ~Jade
> > > > >
> > > >
> > > Morning, Stay at 50, I sure would. sooner or later The Serotonin AD effect should kick in (I know , its always Should) and that is the neuro to get you some happiness back. upping 10mg/s every 2 weeks sounds good. I figured maybe 3 if you needed more time for the side effects to settle down. when I was at 50 and reduced to 40 because of overwhelming side effects it cost me like 3 weeks more waiting. I should of held on and gone to 60 mgs when the 50 wasnt working. Ya those emotions/crying spells are a Parnate issue foresure. I find I'm doing a bit better now, but at my week 8, even tho I was at 60, I sure was an emotional wreck. I believe the higher you go, the happier you get (thats why high doses work good for anxiety people and phobias, the serotonin really kicks in) At lower doses (<60 ?) I believe you feel more task oriented and feelings. Serotonin numbs alot of people. I'm probably going to go to 70mgs/day soon for a better responce to anxiety. I wont forget I was alredy on Nardil the day before switching so I know i got away without having many Parnate startup SE's.
> > > ..
> > > Jade I know its been 8 weeks but if you dont get to your sweet dose it will never kick in, just gotta get there, I think your getting there. Ya I would agree with that person startup feelings are really weird, I felt crapoolliioo like you much of the time mixed with manias at dose increases and then I felt Good withh lots of emotions, now I feel OK/good/less emotions. I think 70mgs will bring me more serotonin and happier thoughts for anxiety which is in a way , numbing.
> >
> > *I hope it does, let me know how're your feeling after you do it! I could use some good news :)
> >
> > > talk to you soon.
> >
> > Hey,
> >
> > Thanks for answering my post so quick. I'm really not sure what the he*l is going on. You don't realize how far you've come until BAM a backslide to the beginning which is how I feel except its all the way back to before Parnate and numbness set in.
> > >
> > I don't mean I was functional at all (except during awesome NE highs) but if no one asked much of me, I felt numb to the really bad stuff, not too emotional, sense of humor, that kind of thing (would the word be "lite"?).
> >
> > Starting to think apathy is highly underated. I just want so bad to be me again and I'm afraid I'm gone. I know, probably too deep for a med babble forum. Thanks, and don't leave me, haha, please!!!
> >
> > Oh, couple questions (had to re-read post),
> >
> > If I never could take SSRI's AT ALL, is that bad sign? Shouldn't be ,right, since I've gotten huge rush at start and when upped to 40mg? Also, are you just being nice....or did you really feel like total emotional crap at 8 weeks? Even if you're lying, your so kind to say that, hah.
> >
> > One last thing, thank you SO much for bailing me out with Clipper40, I felt like I made her feel worse. And by the way, what does "one love" refer to? Prov?, you were in the middle of a Bob Marley song? Or you must have meant me. Thats what I'm going with. No worries, (Bob again, ha), I won't tell your girlfriend.
> >
> > OK Friend, I feel better already,
> > I'll be embarressed about all this whining later but thats the beauty of being anonomous! And quit Parnate?? NEVERRRR!!!!!! Augment? Maybe, haha.
> >
> > ~Jade
> >
> Im really Glad your pushing all the way with Parnate until we Finally know if it will work. Its an MAOI It has to work at some point, sooner or later you will(im almost sure) get to 100% MAO Inhibition. There is a blood test available that can show the amount of the MAO Inhibition. 80% is the sweet spot for most but Ive read some people only feel good at 100%. I was not just being nice about the 8 week feeling bad mark. I knew PARnt was working because I felt the AD efffects, but man o man I was having horrendous feelings of sadness, depression, crying, holding my frontal lobe etc.. but it would come and go. When it would go I felt great. Most of the time I knew what would set me off to feeling horrible: thoughts of a dead friend, a lost friend, myself being mentally screwed up, girls (I wont tell my gf about us eh, glad u wont either hahah).
>
> If you couldnt tolerate an ssri, ok. Makes no difference They are completely different. SSRI side effects were just as bad for me, once i could tolerate them they didnt work for me any way. However they made me numb, emotionless, crazy and able to drink like a fish. Parnate is soo different, I have feelings because its not just working on SE but the whole spectrum of neurons. And the higher the dose the more neurons it will increase leaving your brain in a heightened state all around, not just Serotonin.
>
> As for apathy and ahendonia(i think its spelt) Parnate is top choice along with Wellbutrin and Effexor(effexor for some people.. its only an ssri until you really ramp up the dose to 300+mg/day , then it begins to hit NORE/DA)
>
> K last lil coment here b4 i write too much.. I really believe Parnate takes a long time to settle. I hit my sweet spot at 60mgs/day it took 10 days at that dose, Then BAM it kicked in. That was November 3rd. in the last 4 weeks its gone from good to emotional to sad to overemotional to mania's and now its calming down. I want some more Anxiolytic action so 70mgs I MAY go (thats my hypothesis that the higher dose, the more SE action, which is just what I need for anxiety).
>
> One love was what my best friend used to say all the time.. Now that he's gone we all wonder what it really ment when He'd yell it out. I think the "one" was the person he was saying it to and he was giving out the love to ya.. ill never know but it sure sounded cool to hear him yell it at the end of a night or welcoming pple. He died in April from too many street drugs that led him to a river to drown. im dealing with it but it sent me psychotic twice. But Jade, whats cool is that Parnate makes me feel normal when I think of it now, yes still over the top with emotions but Im not dull, The sad feeling is right for the thought of him, gives me a very human chill..( ya you bet I got tears from that lol.. (hmm Parnate making me human again? or more)
> Hang in there at 50, talk to you soonAh, Okay I'm gonna hang in there at 50mg. I hope I'm as strong as you when I reach the other side. This is my 3rd day on 50mg. Not getting the NE rush yet, but don't feel like COMPLETE he*l anymore either. A little scared for some reason, that it won't work? Or (this is the crazy part) that it will? No more pretending I'm safe in my room and nothing bad ever happens! I'll have to man-up (or woman-up as the case may be) God, I'm such a whimp. I kinda feel like I just wanna get hammered. Maybe I will one of these days, at least it will get me out of the house. And if I don't get some energy soon, maybe I'll just throw some stims in there too. Can you tell I'm tired of this? Can I tell your done hearin it? Yeah!!
Your friend sounds like he was a really awesome guy. I'm sure he felt lucky to have you for a best friend. Now you've got me tearing up. Bye for now.
~Jade
poster:JadeKelly
thread:863385
URL: http://www.dr-bob.org/babble/20081204/msgs/867637.html