Posted by JadeKelly on November 28, 2008, at 17:44:24
In reply to Re: anhedonia along with severe insomnia, posted by X_ander on November 27, 2008, at 0:44:25
> Hey again..
> Jade when you said:
> "What I've noticed is profound early response, energy, cognitive ability restored, interest in going out, seeing people, exercise, etc. Slows way down as does effect past week 2."
> Was that only with respect to bupropion or does it also apply to other drugs you've tried...emsam, parnate etc..
It happened with bupropion, Emsam, Parnate. I also had long run (years) with low dose Ritalin, I always responded well to that but wasn't depressed at that time.
I can't tolerate an SSRI for more than 3 days.
> Also you can't add any antidepressant to parnate or any other MAO inhibitor ...highly dangerous.
Thats what I was told, but people are doing it all the time. I would never think of trying that without consulting my PDoc. I think maybe its a/d's with little ssri activity.
> Bupropion day 7:
> Only taking 150mg today...didn't sleep last nite... slept 5 hours the night before...ugh...bupropion seems to have last it's cognitive buzz..I just feel the same except now I have ears ringing and sleep is more difficult.
> I've read on another forum that bupropion has a honeymoon effect and that you have to stick with it for a few weeks.. anyone else heard or experienced this...?
I experienced the "honeymoon" phase, but that passed a week or so in, then for the next month or so it just made me irritable. I hope I'm not repeating myself (I lost a post to you) my Dad had same response to Wellbutrin that I did. Dropped that. Then tried Cymbalta, nothing. Then Wellbutrin + Cymbalta and he's been in complete remission. Go figure. I think Wellbutrin is a drug that definately has to augment or be augmented by another Dopamine type med for the type of depression were talking about.
I'm doing well so far on Parnate, not remission but I've got a good feeling about it so I'll keep you posted if you haven't tried it. I'm on for 7 weeks now, and I recently increased dose and am feeling pretty decent. Another poster a couple months ahead of me on Parnate is in complete remission, for 6 weeks so far. Same type depression. If you want to know more about Parnate I'll be happy to share my experience this far. Just post to my name.
> I feel like I'm getting nowhere.
It takes a village! I do believe with what I learn here I WILL be in remission, hopefully soon, but if not, I at least know I have other options and I'm not just grasping in the dark (or my PDoc isn't)
Hope that helps,