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glycine + memantine

Posted by desolationrower on September 22, 2008, at 22:21:51

In reply to Glycine and the Glutaminergic Agents, posted by iladvocate on September 22, 2008, at 19:35:38

Iladvocate, do you think this combination would be synergistic. Chronic memantine can increasing glycine bind sites & affinity. IT can also protect against nmda excitotoxicity. In general the combination would increase overall activation, and also preserve signal-to-noise. There appears to be a few positive case reports for memantine.
Of course, these medicines would likely be in the context of 5ht2/d2 antagonism, which is another variable which could throw things off.
-D/R

 

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URL: http://www.dr-bob.org/babble/20080915/msgs/853542.html