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Re: Ixel (milnacipran)

Posted by West on September 2, 2008, at 10:50:04

In reply to Re: Ixel (milnacipran) West, posted by Quintal on September 1, 2008, at 17:17:25


It's interesting comparing the evening wind-down of a couple of beers with a half-tab of zopiclone or zolpidem. I have no moral qualms over either, since i believe we should all be as happy as possible, all the time, and that far from being a sunny life view it is an absolute impreative (i'm something of a david pearce convert). Among my worries would be habituation or addiction, the latter of which admittedly is less of an issue with the Zs than with the benzos despite the common binding site.

I personally feel that for some (and really i mean myself here) those taking antidepressants, particularly reuptake-inhibitors, are often unwittingly disrupting their natural sleep cycles, hence adjunctive sleep meds might be a necessity as long as one is taking them. This poses a problem for both the patient suffering poor sleep and the doctor in charge of prescribing sedatives, since they cannot be given for for periods over two weeks(at least in the UK).
>

It sounds like you do better on anxiolytic drugs. But i must ask one question, mainly out of curiosity rather than disapproval - are you abusing the lorazepam/sleep drugs? I just wonder about whether depression is worsened when the sedative load is increased.

I think the nervous system has a chameleon effect with its environment. Stressful situations, both immediate (as in physical, what surrounds you) and philosophical (the wider life situation) will impact on your levels of stimulation. I found living alone extremely stressful in itself and would always crave turning my brain 'off' with pills. Yeah, so i suppose what i'm saying is that the most useful agents might have as much to do with your situation as your personal biology.
>

I think sleeping is underrated actually, including naps, especially for those with busy minds. Unfortunately sleep deprivation has proved useful in depression, although all of us feel better when we are well rested, so a degree of degree of relativity must be applied when assessing these things. I'm glad tianeptine is helping, i found it lacked the potency i require, though i liked it, especially for its emotion enhancing effects and occasionally weird and magical sensations. Oh and I meant 'social' when i said 'geography' - just post a message to me there and with your address. I think i have been banned from babblemail for trying to sell it before so i can't go down the normal channels.
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Have you confessed to any addictions before? Just curious as this may colour their decision, and NHS docs don't tend to forcibly encourage experimental drug treatment - bonne chance nonetheless, i would be extremely extremely interested in the results. Yes i will keep you updated over the modafinil, though i've taken it before in various guises (from the downright toxic 'modalert' to brand name provigil and australian 'modiodal') and the effects it has engendered are usually far from exciting- Slight mood brightening, minor headache, sometimes feels unpleasant if you are down on your sleep - i predict i will probably take it every other day, or as and when, depending on how rested i feel. Anyway, off for a 2-mile jaunt in the country now, all the best.

West

 

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URL: http://www.dr-bob.org/babble/20080822/msgs/849880.html