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Re: Acetylcholine - Any new developments? SLS

Posted by Dinah on August 21, 2008, at 9:00:46

In reply to Re: Acetylcholine - Any new developments? Dinah, posted by SLS on August 21, 2008, at 2:05:49

Not smart enough to understand any of this. :)

I just did a search on the rhinorrhea, which lead to vascular rhinitis, which led to actylcholine, and all these health issues that I have popped up as being related. IBS, migraines, gerd, a high correlation with anxiety and depression. Then there was this interesting study.

My psychiatrists have always ruled out borderline personality disorder with me, but I've always identified with portions of the descriptions. And I've always thought it was a sloppy diagnosis since surely it involves both an underlying physiological condition, and a characteristic way of coping with it?

The thing that throws me off a bit is that they describe the vascular rhinitis as happening after orgasm, and mine is definitely before orgasm and ends with orgasm.

As far as dopamine goes... Well, I've always been sort of annoyed that depression or anxiety is considered sufficient diagnosis. They have identified a number of different sorts of headaches, caused by different things, and requiring different treatments. The same was true of vertigo. Wouldn't it be at least as true of anxiety and depression? I know there aren't the physical tests that they have for headaches or vertigo. But surely they can find other ways of making more delicate distinctions? Things like comorbidity, or the response to different medications.

It's because of that belief on my part that I'm interested in my enormously positive reaction to antipsychotics, which affect dopamine, and my enormously negative response to norepinephrine affecting medications like Effexor, Wellbutrin, and nortriptyline. Surely this information can help narrow down what exactly is causing anxiety and depression in my case, and therefore give clues in how to treat it.

The only tricyclic I've tried is nortriptyline. I think my current psychiatrist is too conservative to consider a trial of other tricyclics, the ones with a slightly lesser effect on NE perhaps?

Unfortunately, nothing in my googling showed me that there was any treatment targeted at this. The closest is the migraine triptan treatments, but those are pretty specific. However, I understand the whole neurotransmitter stuff so little that I could probably run across the answer to all my problems and not even realize it.

Thanks Scott.

(As I posted this, I wondered whether it should have been posted to the neurotransmitter board, and it occurred to me that if Dr. Bob had adopted your definition of the board, I'd have had less trouble figuring out where it belongs. I wish he had adopted that.)




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