Posted by SLS on August 21, 2008, at 2:05:49
In reply to Acetylcholine - Any new developments?, posted by Dinah on August 20, 2008, at 19:01:10
> I long ago figured out that most of my problems have to do with acetylcholine. IBS, migraine, anxiety. And rhinorrhea with at least some of my sudden migraines, and also just prior to orgasm. If I look into all of these things, they are related to acetylcholine and a hair trigger parasympthetic nervous system. (Am I understanding that right? I'm no expert on neurotransmitters.) I always said that my DSM IV diagnosis should be "nervous system like an overly inbred cocker spaniel".
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> I'm sure I asked about this before, but have they made any inroads in this area? Any new developments?
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> And just as an aside, is there some link between this and my fondness for Risperdal (and Thorazine in my younger days)? I know the antipsychotics target dopamine. Is there some relationship between dopamine and acetylcholine?
You are an incredibly smart woman. Yes, there is a delicate balance between ACh and DA, the disturbance of which has been thought to cause depression. I really don't have much more to offer you in terms of understanding your illness, but I don't doubt your intriguing conclusions will provoke more thought.The other possibility is that you have an overactive sympathetic nervous system. Fight or flight. This usually produces dry mouth, dizziness, rapid heartbeat, blurred vision, reduced peristalsis, and even headache associated with orgasm. Sex prior to orgasm involves the activation of the parasympathetic nervous system. However, orgasm itself is a sympathetic event.
I am confused at this point.
Do tricyclics make things better or worse?
- Scott
poster:SLS
thread:847435
URL: http://www.dr-bob.org/babble/20080814/msgs/847481.html